POS-802 CONTROL OF CALCIUM AND PHOSPHORUS METABOLISM DISORDERS IN HEMODIALYSIS PATIENTS: ASSESSMENT OF ADHERENCE TO KDIGO RECOMMENDATIONS

Chronic renal failure is associated almost constantly with a phospho-calcic metabolism disorder, which significant risk factor for increased cardiovascular mortality and morbidity especially in dialysis patients.The objective of our study was to determine the situation concerning mineral bone disease evaluate degree achievement recommended values KDIGO hemodialysis patients center Charles Nicolle Hospital. In this transversal study, we collected demographic, clinical, biological -including phosphorus, calcium, intact parathyroid hormone (PTH), radiological therapeutic -pertinent medications data Hospital, then compare it targets recommendations. We included seventy-two from (HD) center. Thirty nine females thirty three males sex ratio = 0.84. The median age 52 years. Patients had been on HD 6 years (0.5-30 years). initial nephropathy interstitial nephritis 21 cases, diabetic nephropathies 20 vascular 16 cases not determined 15 cases. Antecedent traumatic fracture noted 10 Fifty-six percent suffer pain thirty-two complain about itching. mean serum calcium 2.07 +/- 0.29 mg/dL average phosphorus level 1,69 0,55 mg/dL. Median eminence PTH (iPTH) 413 (min: 34- max: 2267 pg/mL) PAL 88.5 41- 608 UI/l). Thirty-three presented secondary hyperparathyroidism (PTH > 603 pg/mL). A supplementation prescribed 58% patients. Phosphorus chelating treatments 19% Vitamine D 21% Only 17% parathyroidectomy. compliance phosphocalcic balance indicators chronic compared recommendations 46% calcemia, 37% phosphoremia 41% iPTH.Only seven achieved all targets. No parameters normal range were found nineteen percent. control disorder insufficient. small proportion able achieve simultaneously by KDIGO. Indeed, achieving real challenge considering socioeconomic conditions.